Jean Cruveilhier was an eminent Parisian anatomist who also lived through the mid 19th century (5). Cruveilhier, like Robert Carswell, described the pathology of the lesions seen in MS and although the two men worked independently, their illustrations appeared almost simultaneously (2). Much debate exists as to which illustration was made first. However, Cruveilhier's version, seen in this slide, was not published until 1842 (5).
Cruveilhier's contribution to our understanding of MS goes beyond his description of its pathology as he was the first to record the clinical history of a patient later found to have neuronal lesions. His notes recall that the woman: "had been ill six years without cause … she noticed that the left leg resisted her will to such a degree that she fell in the street" (5).
Cruveilhier described how over several years, the patient developed weakness of both legs and arms, spasms, difficulty in swallowing and visual disturbances. From this he diagnosed 'a lesion of the upper portion of the spinal cord' (5).
New findings show improvement in balance 27 people with multiple sclerosis underwent a 12 week intervention using a Wii balance board. Researchers used an MRI technique called diffusion tensor imaging (DTI) to study changes in the brain. The MRI scans have shown that use of the balance board appears to induce positive changes in brain connections associated with balance and movement. Dr Prosperini lead researcher said 'The most important finding in this study is that a task-oriented and repetitive training aimed at managing a specific symptom is highly effective and induces brain plasticity," he said. "More specifically, the improvements promoted by the Wii balance board can reduce the risk of accidental falls in patients with MS, thereby reducing the risk of fall-related comorbidities like trauma and fractures' Dr Susan Coote, MS Reseacher at the University of Limerick (UL) said, "Balance problems are common for people with MS and lead to problems with walking or falls and injury. Because balance is a complex problem that can be caused by weakness, poor sensation, poor coordination or a combination of all of these, assessment and treatment by a Chartered Physiotherapist is important. The Wii balance board is one promising treatment option that may suit people with relatively minor balance problems and the studies by Prosperini et al have reported interesting results. They reported that the treatment can improve balance and reduce falls, but also showed that changes at brain level were responsible for the improvements seen – this is important as we strive to understand the best ways to address these complex balance problems for people with MS. Other treatments such as physiotherapy based on core stability, dual tasking and sensory inputs can also make a difference as can home programmes. Because MS symptoms vary it is important that we have a range of treatment options to suit the individual nature of MS symptoms." Further reading Irish Examiner article 27/08 PubMed article
Cooking pot with siphon attachment for people with a disability Andrew Fahy, is on the International Entrepreneurship Masters programme in the University of Limerick (UL). He is currently completing a Strategic Commercialisation Project to complete the final stage of a Business Masters. Andrew is researching a potential product and is asking people with MS if they would be interested in a specialised Cooking Pot with Siphon attachment for draining boiled water from a cooking pot more safely; reducing the risk of being burned and to see if this product can benefit people with a disability on a daily basis. The product was orginally designed by a former University of Limerick product designer who's Grandfather has Parkinson's disease. If there is enough interest in buying the product, then the product designer can make a decision to have the product produced and to offer it for sale. What will I have to do? Taking part in this study will involve completing an online questionnaire. It will take approx. 5 minutes and your help will be greatly appreciated. Online questionnaire Please follow the link below: https://www.surveymonkey.com/s/9QVLSQL Closing Date Sunday, 24th August 2014 More information Please email Andrew Fahy firstname.lastname@example.org if you have any questions
Causes, attributions and intervention needs It is known that more than 50% of people with MS experience a fall within a 6 month period. However, there are currently only a few treatments to prevent or reduce falls for people with MS. Dr Susan Coote, who leads this research, is part of an International MS Falls Prevention Research network that will develop a falls prevention programme for people with Multiple Sclerosis. We want to find out about your MS, your falls and what you would like to be included in a falls prevention programme. This will help us to make sure that the programme is based on the needs of the people who will take part in it. What will I have to do? You will be taking part in a one to one telephone interview with a researcher from the University of Limerick. The interview will last between 25-30 minutes. Questions will include simple yes/no questions, multiple choice, open questions and others will be based on a scale. Although it is not necessary for you to be at home, it is advised that you choose a quiet and private place to conduct the interview. The interview will not be recorded; the student will fill in your responses on a data entry sheet throughout the interview. You are not required to answer any questions that you don’t want to and you may withdraw from the study at any stage. Who can participate? People with MS (over 18 years of age) who can walk at least 10 metres with or without an aid and have experienced a fall within the last 3 months can take part in this study. What do I do now? If you would like to take part in this study please contact the research team: Dr. Susan Coote Tel: 061-234278 Email: email@example.com Eve Geraghty Email: firstname.lastname@example.org
Do you have Multiple Sclerosis? Are you living near Galway, Limerick or Cork? If so, you may be suitable to take part in a new free 10-week physiotherapy-led exercise and education intervention MS researchers at the University of Limerick, in collaboration with colleagues in the US, MS Ireland and the Health Research Board have developed a new exercise programme that aims to improve strength and walking ability among people with MS. Who can participate? People with a diagnosis of MS, who are able to walk independently without a mobility aid, are over 18 years, and are currently not physically active, are invited to take part. What do I have to do? The study will involve an initial physiotherapy assessment followed by a 10-week group exercise and education programme (in a community setting in Galway, Limerick or Cork), wherein participants will be asked to attend six 1.5 hour exercise sessions and 3 follow-up assessments after programme completion. This study starts in September 2014. Get in touch For more information please contact Dr. Susan Coote Call (061) 234278 or email: email@example.com
Mice crippled by a version of MS walk after two weeks Researchers in Utah are astonished at the findings of mice who had a condition that mimics the symptoms of human MS, were transplated with human neural stems cells and regained motor skills and were able to walk again after 10-14 days. Six months later, they showed no sign of relapsing. Professor Tom Lane, from the University of Utah, who led the US team, recalled: "My postdoctoral fellow Dr Lu Chen came to me and said ‘the mice are walking’. I didn’t believe her." The study is at an early and gives scientist new ideas for research into potential MS therapies. Further reading Irish Examiner (16/05)
21:00 - 01:00
09:00 - 13:00
15:00 - 17:30
19:00 - 20:00
10:00 - 16:00
10:00 - 12:30
09:30 - 10:30
09:00 - 18:00
South Dublin A...
17:30 - 19:00
10:30 - 11:30